Correlation of Quantitative Diffusion Tensor Tractography with Clinical Grades of Subacute Sclerosing Panencephalitis

Correlation of quantitative diffusion tensor tractography with clinical grades of subacute sclerosing panencephalitis.

BACKGROUND AND PURPOSE SSPE is a persistent infection of the central nervous system caused by the measles virus. The correlation between the clinical staging and conventional MR imaging is usually poor. The purpose of this study was to determine whether tract-specific DTI measures in the major white mater tracts correlate with clinical grades as defined by the Jabbour classification for SSPE. ...

Assessment of white matter damage in subacute sclerosing panencephalitis using quantitative diffusion tensor MR imaging.

BACKGROUND AND PURPOSE Subacute sclerosing panencephalitis (SSPE), a rare progressive degenerative disease, is caused by persistent infection with a defective measles virus. The correlation between the clinical staging and MR imaging is usually poor. The aim of the study was to investigate the role of diffusion tensor imaging (DTI) in the early detection of white matter damage in SSPE in the pr...

Subacute Sclerosing Panencephalitis in Iran

Subacute Sclerosing Panencephalitis in Iran. Clinical and immunoligical characlerisation

[Subacute sclerosing panencephalitis].

Subacute sclerosing panencephalitis is a slowly progressive neurodegenerative disorder occurring in childhood and adolescence and is characterised by dementia, ataxia, myoclonias and other neurological focal signs, with an invariably fatal outcome. The author reviews the subject, focussing on epidemiology, clinical features, measles virus behaviour, host immune reactions, measles prophylaxis an...